Morphological characterization was performed with scanning electron AZD1480 datasheet microscopy and differential scanning calorimetry. The initial modulus, stress and strain at yield, strain at break, and impact toughness of the biodegradable polymer blends were investigated. The properties were described by model,,; assuming different interfacial behaviors (e.g., good adhesion and no adhesion between the dissimilar materials). The results indicated that PCL behaved as a polymeric plasticizer to PLA and improved the flexibility and ductility of the blends, giving the blends higher impact toughness ss. The strain at break was effectively improved by file addition of PCL to PLA, and this was followed by

a decrease in the stress at break. The two biodegradable polymers were proved to be immiscible but nevertheless showed some degree of adhesion between the two phases. This was also quantified by the mechanical property prediction models, which, in conjunction with material property characterization, allowed unambiguous detection of the interfacial

behavior of the polymer blends. (c) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 112:345-352, 2009″
“We present a method to determine the local dielectric permittivity of thin insulating layers. The measurement is based on the detection of force gradients in electric force microscopy by means of a double pass method. The proposed experimental BKM120 mw protocol is simple to implement and does not need any modification of standard commercial devices. Numerical simulations based on the equivalent charge method make it possible to carry out quantification

whatever the thickness of film, the radius of the tip, and the tip-sample distance. This method has been validated on a thin SiO2 sample for which the dielectric permittivity at the nanoscale has been characterized in the literature. We also show how we can quantitatively measure the local dielectric permittivity see more for ultrathin polymer film of poly(vinyl acetate) and polystyrene. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3182726]“
“Background Although radiofrequency thermocoagulation is considered as a primary treatment for most patients with trigeminal neuralgia, neuronavigator-guided percutaneous radiofrequency thermocoagulation has been rarely reported. The object of this study was to assess the clinical value of neuronavigator-guided percutaneous radiofrequency thermocoagulation in the treatment of trigeminal neuralgia.

Methods The radiofrequency thermocoagulation was performed in 100 cases of trigeminal neuralgia. The patients were positioned supine or sitting, under Hartel’s technique (reported by Sweet and Wepsic J Neurosurg 40: 143-156, 1974), by anterior lateral facial approaches. The Gasserian ganglions were acupunctured, assisted by intraoperative CT scanning (3-digital reconstruction) and electrophysiology in order to accurately locate target.

“
“OBJECTIVE: To evaluate maternal and neonatal outcomes of collaborative maternity care for a socioeconomically diverse patient population in a California community hospital.

METHODS: Collaborative practice structure and clinical guidelines were analyzed, as were de-identified electronic medical records for all primiparous women who delivered β-Nicotinamide mw term singletons between 2000 and 2010 (N = 4,426). Demographics, care processes, and perinatal outcomes were compared among women seen prenatally in a private collaborative

practice compared with a Federally Qualified Health Center prenatal clinic run by nurse-midwives.

RESULTS: Evidence-based practices were used to achieve excellent perinatal outcomes. Three quarters of women received intrapartum nurse-midwifery care (74.4%).

Few differences were seen in management or outcomes among women from different prenatal clinics despite significant variation in demographic and clinical characteristics. Private practice patients were older, less likely to be obese, and more likely to speak English compared with counterparts from public health clinics. They were also more likely to use hydrotherapy or epidural analgesia, or experience severe perineal laceration and repair. Overall, pharmacologic pain relief methods were limited: less than a quarter of primiparous women used narcotics (21.2%), epidural analgesia (23.7%), or warm water immersion (23.2%). Labor induction and augmentation, and cesarean delivery rates (12.5%), were similar among groups and low overall.

CONCLUSION: A collaborative Danusertib clinical trial practice of low-tech, high-touch care results in high-quality maternity services. The care model holds promise for replication to address health disparities by limiting obstetric interventions and warrants further investigation with regard to associated costs and resultant outcomes.”
“Rationale: Rapid response teams (RRTs) are intended to stabilize deteriorating patients on the ward, but recent studies suggest that RRTs may also improve end-of-life care (EOLC). We sought to study

the effect of introducing an RRT on EOLC at our institutions, and compare the EOLC care received by patients who were consulted by the RRT with that of patients who were not consulted by the RRT.

Methods: Retrospective review of 450 consecutive Temsirolimus research buy deaths at 3 institutions. We compared demographic factors and EOLC received before (2005) and 5 years after (2010) the introduction of an RRT. We also compared these same factors for patients who died in 2010 with and without RRT consultation.

Results: There were no differences in the proportion of patients who had Patient/Family Conferences or orders to limit life support on the ward between 2005 and 2010. Although the RRT was consulted for 30% of patients eligible to be seen by the RRT, the RRT was involved in only 11.1% of Patient/Family Conferences that took place on the ward.

There was a significantly high (P

= .012) prevalence of subclinical hypothyroidism (26%) in those receiving valproate monotherapy compared with healthy controls selleck inhibitor (7.7%). Median duration of valproate therapy was significantly higher (P = .039) in the subclinical hypothyroidism group (21 months, range 6-36) compared with those without subclinical hypothyroidism (14 months, range 6-25). Results of the present study suggest higher prevalence of subclinical hypothyroidism in children with controlled epilepsy on long-term valproate monotherapy.”
“We have demonstrated magnetic properties of single 3d transition metal (TM) atom (from Sc to Ni) adsorbed on the surface of graphene and benzene in the framework of relativistic density functional theory. Binding energies, spin and

orbital magnetic moments, and magnetic anisotropy energies (MAE) of the TM-graphene and TM-benzene structures were determined. Our calculations show that magnetic moments of most 3d TM atoms added to the surface of graphene PKC inhibitor and benzene are partially quenched when compared to their free atomic state. We found very robust orbital moments for Co adatom on graphene and benzene and Cr adatom on benzene compared to the almost quenched orbital moments for the other 3d TM adatoms. It is also found that Co-graphene and Co-benzene show very large magnetic anisotropy energies, with easy axis perpendicular to the graphene plane and aligned to the C6 rotation axis of the benzene molecule, whereas the other 3d TM adatoms behave like a soft magnet. (C) 2011 American Institute of Physics.

[doi:10.1063/1.3636112]“
“The purpose of this study was to determine average penile length and to investigate the relationship between penile length and somatometric parameters in a group of young, healthy Turkish men. A total of 1132 men were included in the study. The age, height and weight of the subjects www.selleckchem.com/products/blebbistatin.html were recorded. Penile length was measured in both flaccid and stretched states. The correlation between penile length and somatometric parameters was analysed. The mean age of the subjects was w20.3 +/- 0.9 years. The mean penile length in flaccid and stretched states was 9.3 +/- 1.3 and 13.7 +/- 1.6 cm, respectively (P < 0.001). There was a positive correlation between flaccid and stretched penile length (r=0.800, P < 0.001). The mean testicular volume was 22.0 +/- 2.8 cm(3). A weak positive correlation was detected between penile length and mean testicular volume (r=0.143 for flaccid penile length and r=0.140 for stretched penile length, P < 0.001 for both). Similarly, weak positive correlations were found between penile length (both flaccid and stretched) and height, weight and body mass index, respectively (P < 0.001, for all). These results demonstrate that somatometric parameters are correlated with penile length. We believe that further studies would provide more information about the causal relationship. Asian Journal of Andrology (2011) 13, 339-341; doi:10.1038/aja.

Reticulin and NM23 have been studied in this context. The pattern of reticulin staining in melanomas surrounds groups/nests of melanocytes but individual cells in benign nevi. SNX-5422 mw NM23, a metastasis-suppressor gene, has an association with metastatic potential in melanomas and some carcinomas. Twenty-eight cases (14 cases of metastatic melanoma to lymph nodes and 14 cases of lymph node nevus rests, all confirmed with Melan-A staining) were stained with reticulin and NM23. The pattern of

reticulin staining was reported as surrounding groups if staining was noted in approximately 5-10 melanocytes in greater than 50% of the lesion but was otherwise reported as surrounding individual melanocytes. Cytoplasmic staining was considered to represent reactivity for NM23. Reticulin staining around groups of melanocytes was identified in all 14 cases of metastatic melanoma. Regarding nodal nevus rest cases, 12 of 14 cases (86%) demonstrated staining P5091 cell line around individual melanocytes, whereas in 2 cases, reticulin surrounded melanocytic groups. NM23 staining was equivocal in all cases. Reticulin staining reliably invests groups of melanocytes in cases of metastatic melanoma, whereas in nodal nevus rests, it predominantly surrounds individual melanocytes. NM23 demonstrated no discriminatory value in this analysis. In cases in which a collection

of melanocytes is present within a lymph node, reticulin deposition around individual melanocytes supports a diagnosis of lymph nodal nevus rest.”
“Background: This work was planned to check for the association of polymorphisms related to methylenetetrahydrofolate reductase (MTHFR) and angiotensin converting enzyme LY3039478 research buy (ACE) genes with overweight/obesity among Saudi subjects from Qassim region.

Methods: This work included 130 subjects having overweight or obesity and 111 normal controls. Their age mean +/- SD was 27 +/- 9.8

and 24 +/- 8.8 years respectively. Their DNA was analyzed for polymorphisms of MTHFR; 677C/T and 1298 A/C and ACE; I/D genes using real-time PCR.

Results: Genotype and allele frequencies of studied polymorphisms in cases of overweight/obesity showed no significant statistical difference compared to that of controls. However, on analysis of body mass index (BMI), cases showed slightly higher but statistically nonsignificant mean +/- SD values among those carrying the mutant MTHFR 677 T allele (CT + TT vs. CC, 30.7 +/- 4.5 vs. 29.9 +/- 4.9), 1298 C allele (AC + CC vs. AA, 29.9 +/- 4.1 vs. 29.7 +/- 5.5) and ACE D allele (ID + DD vs. II, 30.0 +/- 5.1 vs. 29.1 +/- 2.8). In addition controls having the DD and ID genotypes showed higher statistically significant values of BMI than those of the II genotype (22.0 +/- 1.9, 21.7 +/- 2.6 and 19.5 +/- 2.3 respectively, p < 0.05).

Conclusion: There is no solid association of polymorphisms related to MTHFR and ACE genes with non-complicated overweight or obesity among Saudi subjects from Qassim Region.

The

origins of discrepancies in the interface trap densities determined from the different methods are discussed. Commonly observed features in the CV characteristics of high-k/In(0.53)Ga(0.47)As interfaces are interpreted and guidelines are developed to obtain reliable estimates for interface trap densities and the degree of Fermi level (un) pinning for high-k/In(0.53)Ga(0.47)As interfaces. (C) 2010 American Institute of Physics. [doi:10.1063/1.3520431]“
“Evaluation of: Lunde CS, Hartouni SR, Janc JW, Mammen M, Humphrey PP, Benton BM: Telavancin disrupts the functional integrity of the bacterial membrane through targeted interaction with the cell wall precursor lipid II. Antimicrob. Agents Chemother. 53, 3375-3383 (2009). It has been selleck chemical previously demonstrated that telavancin has a dual mechanism of action: inhibition of the transglycosylation process of peptidoglycan cell wall synthesis by the formation of a complex with the D-alanyl-D-alanine precursors; and depolarization of the bacterial membrane. In this article

the mechanism by which telavancin disrupts the bacterial cell membrane was studied by Lunde and colleagues using a variety of Staphylococcus aureus Galardin Proteases inhibitor strains. The authors demonstrated that telavancin-induced depolarization requires both the AZD2014 concentration presence of lipid II as well as an interaction between telavancin and D-alanyl-D-alanine residues. The authors were also able to show that telavancin’s depolarization effect on membrane potential occurs in diverse S. aureus strains including those with decreased susceptibility to vancomycin and daptomycin. This study takes a significant step forward in our understanding of the concentration-dependent bactericidal activity of telavancin, a drug recently approved for use in skin and skin structure infections caused

by Gram-positive cocci.”
“Background and aims: Hyperglycemia and diabetes are associated with increased formation of advanced glycation end products and enhanced oxidative stress, leading to the progression of diabetic vascular disease. We have investigated the mechanisms by which AGE-modified bovine albumin (AGE-BSA) induces reactive oxygen species (ROS) generation, leading to nuclear factor-erythroid 2-related factor (Nrf2) dependent induction of the antioxidant genes heme oxygenase-1 (HO-1) and NADPH: quinone oxidoreductase 1 (NQO1) in bovine aortic endothelial cells.

Methods and results: AGE-BSA (100 mu g ml (1), 0-24 h), but not native BSA, elicited time-dependent increases in ROS generation, Nrf2 nuclear translocation and enhanced mRNA and protein expression of HO-1 and NQO1, but not glutathione peroxidase-1.

The rats were anesthetized and paralyzed. Pulmonary function tests were performed at baseline and after varying doses of acetylcholine. Bronchoalveolar lavage fluid and lung tissues were examined. Results: Zileuton had beneficial effects on pulmonary

function, airway inflammation and ASM remodeling in the OA-zileuton group compared to the OA-saline group. Zileuton inhibited an OA-stimulated increase in ASM by inhibiting hypertrophy, hyperplasia and increased extracellular matrix via the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, thereby reducing cyclin D1 expression and attenuating bronchial HIF inhibitor hyperresponsiveness. Conclusion: OA increases airway inflammation and ASM mass. Zileuton effectively prevents bronchial hyperresponsiveness, airway inflammation and ASM remodeling in sensitized rats through the PI3K/Akt pathway, which reduces cyclin D1 expression. (C) 2013 S. Karger AG, Basel”
“Recent Studies suggested a role of appetite regulating peptides like leptin and ghrelin in alcohol dependence and particularly in the neurobiology of alcohol craving. Aim of the present study was to investigate click here alterations of the adipocytokines adiponectin and resistin in alcohol-dependent patients. We analyzed a sample of 88 patients

at admission for alcohol detoxification and after I week of withdrawal treatment in comparison to 89 healthy controls. Adiponectin and resistin serum levels were measured using commercial ELISA kits. The extent of alcohol craving was obtained using the obsessive Compulsive Drinking Scale (OCDS). Adiponectin and resistin serum levels were significantly elevated in patients with alcohol dependence at both dates (admission and after I week of treatment) compared to

healthy controls. Adiponectin decreased significantly during the Course of withdrawal (T = 3.44, p = 0.001) while resistin Serum levels showed a slight increase (T = -1.83, p = 0.071). selleck inhibitor In a multivariate approach the extent of alcohol craving was significantly associated with adiponectin but not with resistin serum levels in male patients (Beta = -0.255, p = 0.025). Results for female patients were not significant, Our findings provide first evidence for an alteration of file adipocytokines adiponectin and resistin during alcohol withdrawal. Furthermore, adiponectin may be involved in the neurobiology of alcohol craving, possibly via its effects oil the hypothalamic circuits. (C) 2008 Elsevier Ireland Ltd. All rights reserved.”
“BACKGROUND

Botulinum toxin type A (BoNTA) is commonly injected to treat facial wrinkles. Complications include pain, erythema, bruising, and potential infection. RT001 Botulinum Toxin Type A Topical Gel (RT001) is under development for the treatment of lateral canthal lines (LCLs).

OBJECTIVE

To assess the efficacy and safety of RT001 for the treatment of LCLs using a randomized, double-blind, repeat-dose, placebo-controlled study design.

(C) 2014 European Society check details for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.”
“BACKGROUND: This research has assessed the impact of sulfate accumulation on the performance of two biofilters treating CS2. Both biofilters were packed with a pelletized organic fertilizer and operated in downflow mode (Biofilter A) and flow reversal mode (Biofilter B). The performance of the biofilters

after an excessive accumulation of sulfate has also been evaluated. RESULTS: The excessive accumulation of sulfate and the reduction in the packing material’s moisture content resulted in a decrease in the initial high removal efficiency recorded during the first 50 days (approx.) of operation in both biofilters. A recovery strategy based on mixing and washing the packing material led to a sustained RE of 40 +/- 9% and 62 +/- 11% for Biofilters A and B, respectively. Both biofilters recovered their initial performance after irrigation. A high CO2:EC ratio suggested

that secondary oxidation reactions related to heterotrophic bacteria occurred in both bioreactors. The maximum elimination capacity (ECmax) recorded in Biofilters A and B was 11.6 and 16.6 g CS2 m-3 h-1, respectively. CONCLUSIONS: This study confirmed the capacity biofilters treating CS2 have to recover after sulfate accumulation episodes and the importance of optimized irrigation strategies. The benefit of the flow reversal operating mode was highlighted. Copyright (c) 2012 Society of Chemical Industry”
“Objectives: The “”tissue AS1842856 solubility dmso oxygen saturation (StO(2)) foot-mapping”" method was developed using a non-invasive near-infrared tissue oximeter monitor to classify the foot regions as ischemic and non-ischemic areas. The purpose of this study was to evaluate StO(2) foot-mapping as a reliable method to detect ischemic areas in the feet of patients with critical limb

SBE-β-CD ischemia (CLI), and to compare the results with assessments from the angiosome model.

Methods: The foot areas of 20 CLI patients and 20 healthy controls were classified into four regions: (1) 0 <= StO(2) < 30%, (2) 30 <= StO(2) < 50%, (3) 50 <= StO(2) < 70%, and (4) 70 <= StO(2) <= 100% to perform StO(2) foot-mapping. Each area occupancy rate was compared between the two groups, and the threshold StO(2) value for detecting ischemia was set. Next, the locations of ulcers (in 16 patients) were compared to the predicted ischemic regions by the StO(2) foot-mapping and by the angiosome model and angiography.

Results: In regions (1) and (2) (StO(2) < 50%), the area occupancy rate was significantly higher in the CLI group and almost zero in the control group, so that the threshold StO(2) value for detecting ischemia was set at 50%. The locations of ulcers were compatible with StO(2) foot-mapping in 87.5% of the cases (14/16), while they were compatible with the assessment from the angiosome model in 68.8% of the cases (11/16).

This behavior could be attributed to probable chain scission of long polymer chains as a result Of the high shear and elongation forces that arose on the disc surface. INCB024360 supplier (C) 2009 Wiley Periodicals, Inc. J Appl Polym

Sci 113: 709-715, 2009″
“Background Topical treatment with vitamin C has been used to treat photoaged skin and as a skin whitener, but no standard procedure exists for percutaneous delivery. Objective To compare skin histology and the permeation of ascorbic acid 2-glucoside (AA2G) after fractional and conventional carbon dioxide (CO2) laser pretreatment. Methods The effect on porcine skin of treatment with different strengths of fractional and conventional CO2 laser treatment was examined using scanning electron microscopy and transmission electron microscopy. Permeation of AA2G through porcine skin was tested in vitro using a Franz diffusion chamber. In vivo changes in fluorescein thiocyanate permeability in nude mice were examined using

confocal laser scanning microscopy. Results Fractional CO2 laser treatment with four or fewer passes caused less disruption than conventional laser treatment at the same fluence. AA2G permeation GW4869 manufacturer using four passes of fractional laser treatment was similar to that seen with conventional CO2 laser treatment of the same fluence. Changes in permeability and in depth of permeation were higher with conventional than fractional laser treatment. Conclusion Fractional CO2 laser treatment can cause similar transdermal delivery of AA2G to conventional laser treatment with less skin disruption and a different pattern of histologic change.”
“Background. Non-tumoral causes constitute a major group of childhood hypopituitarism. The structural abnormalities of the stalk and the pituitary gland correlate with number and severity of concurrent hormone deficiencies. We describe clinico-radiological correlates in patients with non-tumoral hypopituitarism.

Patients GW4869 purchase and Methods: Thirty-one children (23 boys) with congenital hypopituitarism, aged 1-17 years, with a peak GH levels of <7 ng/ml after two pharmacological

stimuli (insulin induced hypoglycemia [IIH] and clonidine) were included in the study. MRI tetrad of absent or hypoplastic pituitary, empty sella, redundant or absent stalk and absent/ectopic posterior pituitary bright spot (EPPBS) was considered as a radiological diagnostic criterion and these abnormalities were correlated with number of hormone deficiencies, severity of GH deficiency and mode of presentation at the time of delivery.

Results: Twenty (66%) children had vertex presentation, nine breech, and two children were delivered by lower segment Cesarean section (LSCS). Seven (78%) out of nine in the breech delivery group, 14 (70%) out of 20 in the vertex group and one out of two (50%) in the LSCS group had multiple pituitary hormone deficiencies (MPHD) (p = 0.665).

Conclusion: The increase in bone volume combined with the increase in TrTh in endplate VOIs strongly suggest that the subchondral endplate condenses to a more dense structure in degenerated IVDs. This may negatively influence the diffusion and nutrition of the IVD. The endplate differences between intact and mild degenerative IVDs (grade II) indicate an early association of subchondral endplate changes with IVD degeneration. (C) 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.”
“Objective: Report a case of loss

of cochlear implant benefit after cisplatin therapy to treat osteosarcoma. Examine the implications for the loci of cisplatin-associated cochleotoxicity.

Study Design: Retrospective SYN-117 case review.

Setting: Tertiary

referral center.

Patients: Single case study.

Intervention(s): None.

Main Outcome Measure(s): Cochlear implant programming levels.

Results: Increase in cochlear implant programming T- and C-levels after cisplatin therapy.

Conclusion: Cisplatin therapy likely affects spiral ganglion cells. It seems that auditory cells other than outer hair cells in the organ of Corti are affected by cisplatin because the hearing sensitivity of this patient with nonfunctioning outer Selleck Fedratinib hair cells declined after receiving chemotherapy. Implications of these findings are discussed.”
“Eucommia ulmoides Oliver is one of the few woody plants producing trans-polyisoprene (TPI or Eucommia rubber). Eucommia fruits contain average 12-17% of TPI, much higher than in leaf or bark. However, commercialization of TPI production from Eucommia fruits is confronted with two major problems: the low yield and high cost of fruit harvest. To develop an economically viable solution to those two problems, we conducted a 9-year study from 1998 GSK3235025 datasheet to 2006 to compare the fruit or leaf production among different training systems (orchard-like model vs conventional model), cultivars (conventional vs new cultivars) and tree densities. Our results showed that the trees grafted with the new cultivar commenced fruiting

about 3 years earlier and produced significantly higher fruit yield over the study period than the non-grafted Eucommia trees. This study also demonstrated for the first time that the orchard system with a tree planting density of 3 m x 3 m and a female proportion of up to 90% yielded 40 times as much fruit as the conventional model without using the new cultivars or 5 times as much as the conventional model using the new cultivar grafted trees. Eucommia orchard in spacing 3 m x 3 m yielded more than 4000 kg ha(-1) fruit in 2006, equivalent to 520 kg ha(-1) of TPI, similar to low yield of cis-1,4-polyisoprene (CPI) from Hevea brasiliensis plantations. The relatively low tree height in the orchard system also significantly reduced the cost of fruit harvest, as compared to the conventional model.

LOS varied between 30 and 120 days. None of the patients died.

Conclusion

The location of leakage, and the presence or absence of an intraabdominal drain are determining factors for its treatment. UGI radiography with contrast media and gastroscopy are comparable and superior to standard CT scan. Stent graft application is www.selleckchem.com/products/azd5153.html a promising therapy in case of proximal leakage; re-suture or resection of the staple line are possible solutions in case of a distal leak.”
“Background and objectives: Acid-base status in acute severe asthma (ASA) remains undefined; some studies report complete absence of metabolic acidosis, whereas others describe it as present in one fourth of patients or more. Conclusion discrepancies would therefore appear to derive from differences

in assessment methodology. Only a systematic approach centering on patient clinical findings can correctly establish true acid-base disorder prevalence levels. Methods: This study examines acid-base patterns in ASA (314 patients), taking into account both natural history of disease and treatment, in patients free of other diseases altering acid-base status. Data were collected from patients admitted for ASA without prior history of chronic bronchitis, emphysema, kidney or liver disease, heart failure, uncontrolled diabetes mellitus or gastrointestinal illness. Informed consent was obtained for all patients, after study protocol approval by the Institutional Review Board. Results: Arterial blood gases, plasma electrolytes, lactate levels, and FEV1 were measured on arrival. ACY-738 Severe airway obstruction was found with FEV1 values of 25.6 +/- 10.0%, substantial hypoxemia (PaO2 66.1 +/- 11.9 mmHg) and increased

A-a O-2 gradient (39.3 +/- 12.3 mmHg) breathing Stem Cell Compound Library room air. While respiratory alkalosis occurred in patients with better preservation of FEV1, respiratory acidosis was observed with more severe airway obstruction, as was increased lactate in the majority of patients, independent of PaO2 and PaCO2 levels. Conclusions: Predominant acid-base patterns observed in ASA in this patient population included primary hypocapnia, or less frequently, primary hypercapnia. Lactic acidosis occurred in 11% of patients and presented consistently as a mixed acid-base disorder. These findings suggest lactic acidosis results from the combined effects of both ASA and medication-related sympathetic effects.”
“Surgical correction of hiatal hernia (HH) during bariatric surgery has been found to improve patient outcomes and decrease reoperation rate. Although barium esophagram is more sensitive than endoscopy for detection of HH, accurate preoperative diagnosis remains a challenge. The aim of this study is to determine whether diagnostic accuracy improves by utilizing right anterior oblique (RAO) esophagram technique instead of the commonly used upright technique when comparing to the gold standard of intraoperative detection.