The α level for all analyses was set as P < 0.05. Results Twenty-one Advanced Paramedics were approached and each consented to participate, and were enrolled into the study. Scenario 1 – Normal airway scenario The duration of the first and of the successful tracheal intubation attempts were significantly greater with the Truview® laryngoscope Doxorubicin datasheet compared to the Macintosh and Airtraq® laryngoscopes. There were no significant differences in the duration of the first or the successful tracheal intubation attempts between the Macintosh Inhibitors,research,lifescience,medical and Airtraq® devices

(Table ​(Table11 and Figure ​Figure3).3). All 21 AP’s successfully intubated the trachea with the Macintosh laryngoscope, compared to 20 with the Airtraq® and 19 with the Truview® laryngoscopes (Table ​(Table11). Figure 3 Box plot representing the duration required to successfully intubate the trachea with each device in each scenario tested. The data Inhibitors,research,lifescience,medical are given as median and interquartile range,

with the bars representing the 10th and 90th centile. * Indicates significantly … Table 1 Data from the easy laryngoscopy scenario There were no between group differences in the number of intubation attempts required with each device. The number of optimization manoeuvres required was Inhibitors,research,lifescience,medical significantly lower with the Airtraq® group, and significantly greater with the Truview® group, compared to the Macintosh group. The severity of dental compression was significantly greater with the Macintosh group compared to both the

Airtraq® and Truview® devices (Table ​(Table1).1). The participants found the Inhibitors,research,lifescience,medical Truview® significantly more difficult to use than the other laryngoscopes in this scenario. There was no significant difference in the difficulty of device use between the Macintosh and Airtraq® devices (Figure ​(Figure44). Inhibitors,research,lifescience,medical Figure 4 Box Plot representing the user rated degree of difficulty of use of each instrument in each scenario tested. The data are given as median and interquartile range, with the bars representing the 10th and 90th centile. * Indicates significantly different … Scenario 2 – Manikin with cervical collar The duration of the successful, but not the first, tracheal intubation Ergoloid attempt was significantly longer with the Truview® compared to the Macintosh and Airtraq® laryngoscopes. There was no significant difference in the duration of these attempts between the Macintosh and Airtraq® devices (Table ​(Table22 and Figure ​Figure3).3). All AP’s successfully intubated the trachea with the Macintosh and Airtraq® laryngoscopes, compared to 20 with the Truview® laryngoscope (Table ​(Table22). Table 2 Data from the cervical immobilization scenario There were no between group differences in the number of intubation attempts required with each device.